Composition

Each 100 gm contains

Halfa bar extract 6 mg ( Equivalent to 8 mg Proximadiol).
Hexamine 6 gm.
Piperazme citrate 1 gm .

Properties

PROXIMOL COMPOUND acts as an efficient preparation for expulsion of ureteric calculi by the unique action of its content of proximadiol (present in the purified extract of Halfa bar) which produces ureteric dilatation while increasing the propulsive movement of the smooth muscles of the ureter, helping the expulsion of the calculi.

PROXIMOL COMPOUND also dissolves uric acid and urate crystals prevents their deposition in the urinary tract. and these effects are mainly achieved by the action of Piperazine citrate .

In addition to the fore-mentioned properties, PROXIMOL COMPOUND acts as an effective urinary antiseptic due to its content of Hexamine which liberates formaldehyde in the urine. Formaldehyde possesses antibacterial activity against many bacteria responsible for urinary tract infections.

Indications

As propulsive for ureteric stones .
presence of excess uric acid and urate crystals in urine.
Urinary tract infections e.g. pyelitis , cystitis , urethritis .

Side effects

Rarely nausea may occur .

Contraindications

Hypersensitivity to any of the components.

Impairment of renal or hepatic function.

Use in Pregnancy

During pregnancy its safety has not been Justified so it is better to be avoided during the first trimester as many other new drugs.

Precautions

Some of the rarely used sulphonamides.e g sulphamethizole and sulpathiazole, may form Insoluble precpitate with the liberated formaldehyde In the urine, so, hexamine containing

preparations are not recommended to be used concurrently with these sulphonamides.

Dosage

2 teaspoonfuls (or 1 sachet) in half glass of water three times daily after meals .

Proximol – patient information leaflet