TOMAZINE_ for allergic conditions

TOMAZINE is indicated to treat allergic conditions responding to a histamine H1 receptor antagonist. 

  • Respiratory : Allergic rhinitis (seasonal, perennial). hay fever.
  • Cutaneous : Allergic skin conditions associated with pruritus e.g. urticaria.

Dosage and Administration

  • Adults and children older than 12 years old: one tablet daily. 
  • Children 6 to 12 years old: Half a tablet twice daily or one tablet once daily. 

TOMAZINE composition: Each tablet contains: Cetirizine 10 mg.

Overdosage

In adults drowsiness may be a symptom of overdosage. in children agitation may occur.Overdose treatment should be symptomatic and supportive with gastric lavage.

Side Effects

  • Mild and transient side effects such as: Headache. dizziness. drowsiness. agitation, dry mouth, increased appetite, nervousness and gastro-intestinal discomfort.
  • Hypersensitivity reactions including -skin reactions and angio-edema may develop.
  • Consult your Physician or Pharmacist if any side effects are observed.
TOMAZINE 10MG tablets- alfacure
TOMAZINE 10MG tablets- alfacure

TOMAZINE- FAQ

What time of day should I take TOMAZINE? TOMAZINE tablets can be taken any time of the day. Always follow the label directions.

Should I take TOMAZINE with food? This medicine( cetrizine tablet/ TOMAZINE tablet) can be taken with or without food.

Can I safely take TOMAZINE for allergy, if I have heart disease or high blood pressure? TOMAZINE contains Cetirizine only with no decongestant. This medicine does not raise blood pressure, create palpitations or interfere with some other heart medications. TOMAZINE should be safe for most patients with heart disease or high blood pressure.

Does TOMAZINE cause weight gain? Newer allergy drugs, including cetirizine (TOMAZINE), fexofenadine (Telfast) and loratadine (Claritin), are less likely to cause weight gain.There are other side-effects that antihistamines like TOMAZINE will cause as well, but gaining weight is typically one people don’t expect.

Is it OK to take TOMAZINE everyday? Yes, you can take TOMAZINE daily and long term. It is an antihistamine used to treat allergy symptoms. If your symptoms are seasonal or you have allergy symptoms occasionally, then it is taken daily when required.

Can TOMAZINE cause constipation? Certain antihistamine drugs like Claritin, TOMAZINE, and Telfast that are available over the counter to treat allergy symptoms may stop you up. They belong to an even larger class of medications known as anticholinergics, which all have the possible side effect of causing constipation.

Does TOMAZINE make you drowsy? TOMAZINE contains cetirizine. It is a second-generation antihistamine. It is  less likely to make a person feel drowsy or otherwise affect alertness than older, first-generation antihistamines.

Can TOMAZINE be used for itchy skin? TOMAZINE is suitable for most hayfever allergy symptoms. It helps ease symptoms such as sneezing, itchy and runny nose and itchy throat. It is also suitable for those suffering with symptoms of itchy skin rash or hives (urticaria) associated with allergies.

Is it better to take TOMAZINE at night or in the morning? Cetirizine/ TOMAZINE can be taken at any time of the day. In most people it is non-sedating, so they take it in the morning. However, a percentage of people do find it to be sedating so if it does make you drowsy it is best to take it in the evening. TOMAZINE can be taken with or without food.

Properties

TOMAZINE is an anti-allergic agent with a histamine H1 receptor antagonism devoid of any significant anticholinergic and anti-serotonin effects. Cetirizine also reduces eosinophil recruitment induced by antigen-antibody reaction. Peak blood levels are reached within one hour after oral administration of Cetirizine. The terminal half life is approximately 10 hours in adults, 6 hours in children aged 6 to 12 years. Plasma levels are linear related to the dose given. A high proportion of Cetirizine is bound to human plasma proteins.

Contraindications

  • TOMAZINE is contraindicated in patients with known hypersensitivity to any of its components.
  • Not to be given for lactating women since the active ingredient is excreted in breast milk, and not in pregnancy.
  • This medication should not be used for the treatment of cough and cold symptoms in children under 6 years of age. 

Precautions

Precautions and dosing adjustment is necessary in patients with moderate or sever renal impairment, dialysis patients and in patients with hepatic impairment.

Interactions with other drugs

  1. Studies with diazepam and cimetidine have revealed no evidence of interactions.
  2. No drug interactions have been found with theophylline (at low dose), azithromycin, pseudoephedrine. ketoconazole. or erythromycin.
  3. A small decrease in the clearance of Cetirizine is caused by a 400 mg dose of theophylline.
  4. Concomitant use with CNS depressants and anti-cholinergics increases their toxicity. 

Warnings

Avoid driving a car, operating potentially dangerous machinery, drinking alcohol or using CNS depressants concurrently with Cetirizine, due to additional reduction in alertness and additional impairment of CNS performance.

Patient Information Leaflet

ENG - Patient Information Leaflet
Cetrizine – Patient Information Leaflet

Categories and tags: R06AE07, Cetirizine, Piperazine derivatives, ANTIHISTAMINES FOR SYSTEMIC USE, ANTIHISTAMINES FOR SYSTEMIC USE, RESPIRATORY SYSTEM.

تومازين- معلومات باللغة العربية
تومازين- معلومات باللغة العربية

Alternative to this medicine: Artiz, Tomazine, HISTAZINE-1, HISTA CHEW, EPIRIZINE, CETRITIN tablets, CETRAK tablets, Alerid tablets.


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